MyBioSource.com's Rabbit anti-human Paired box protein Pax-4 polyclonal Antibody(PAX4) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The Rabbit anti-human Paired box protein Pax-4 polyclonal Antibody(PAX4) was generated using PAX4 as the antigen and it reacts with Human, and Mouse.
Description
Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity